Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | GFER | P55789 | 1/20 | 0.70 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 4/20 | 0.62 |
| ▸ | CA9 | Q16790 | 4/20 | 0.62 |
| ▸ | CA1 | P00915 | 3/20 | 0.62 |
| ▸ | CA4 | P22748 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7580082 | 0.88 | ALDH1A1 (0.60) | ALDH1A1GAAGFERFFAR4LMNA | |
| SCHEMBL16671925 | 0.88 | APP (0.61) | ALDH1A1GAAGFERFFAR4LMNA | |
| SCHEMBL7580401 | 0.86 | CA1 (0.70) | ALDH1A1GAAGFERFFAR4LMNA | |
| SCHEMBL29048726 | 0.85 | FFAR4 (0.77) | ALDH1A1GAAGFERFFAR4LMNA | |
| SCHEMBL2367811 | 0.85 | APP (0.62) | ALDH1A1GAAGFERFFAR4LMNA | |
| SCHEMBL5956125 | 0.85 | ALDH1A1 (0.59) | ALDH1A1GAAGFERFFAR4LMNA | |
| SCHEMBL7589428 | 0.85 | FFAR4 (0.67) | ALDH1A1FFAR4LMNAPOLBMAPT | |
| SCHEMBL7590523 | 0.85 | LMNA (0.69) | ALDH1A1GAAGFERFFAR4LMNA | |
| SCHEMBL7588784 | 0.85 | ALDH1A1 (0.59) | ALDH1A1GAAGFERFFAR4LMNA | |
| SCHEMBL7589780 | 0.84 | ALDH1A1 (0.69) | ALDH1A1GAAFFAR4MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |