SCHEMBL29048904

SCHEMBL29048904

OP(OC(c1ccccc1)(c1ccccc1)c1ccccc1)OC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.40
ALDH1A1 P00352 3/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.37
KCNN4 O15554 3/20 0.36
TSHR P16473 2/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 3/20 0.34
CYP3A4 P08684 2/20 0.34
CYP2C9 P11712 2/20 0.34
KCNH2 Q12809 1/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
PTPN1 P18031 1/20 0.33
CYP2C19 P33261 1/20 0.33
CYP2D6 P10635 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
CES1 P23141 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3969286 0.85 KIF11 (0.40) KIF11ALDH1A1ALOX15MAPK1KCNN4
SCHEMBL28322992 0.85 KIF11 (0.34) KIF11ALDH1A1ALOX15MAPK1KCNN4
SCHEMBL1764122 0.81 KIF11 (0.42) KIF11ALDH1A1ALOX15MAPK1KCNN4
SCHEMBL14690531 0.79 KIF11 (0.43) KIF11ALDH1A1ALOX15MAPK1KCNN4
SCHEMBL3809634 0.76 ALDH1A1 (0.58) ALDH1A1ALOX15MAPK1KCNN4KMT2A
SCHEMBL27727294 0.75 ELANE (0.39) ALDH1A1ALOX15KCNN4KMT2AMEN1
SCHEMBL4304144 0.75 KIF11 (0.45) KIF11ALDH1A1ALOX15MAPK1KCNN4
SCHEMBL1764124 0.73 KIF11 (0.43) KIF11ALDH1A1ALOX15MAPK1KCNN4
SCHEMBL8586539 0.71 KIF11 (0.42) KIF11ALDH1A1ALOX15MAPK1KCNN4
SCHEMBL297104 0.70 ALDH1A1 (0.56) KIF11ALDH1A1ALOX15MAPK1KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119569733-A USP1 inhibitor and preparation method and application thereof 成都微芯药业有限公司 2025-03-07 CN disclosed
CN-116354825-A Synthetic method of methyl dichlorochrysanthemate 江苏优嘉植物保护有限公司 2023-06-30 CN disclosed