SCHEMBL28322992

SCHEMBL28322992

OP(Oc1ccccc1)OC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.34
ALDH1A1 P00352 3/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 3/20 0.32
LTA4H P09960 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPK1 P28482 1/20 0.31
CA5A P35218 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KCNN4 O15554 2/20 0.31
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
KCNH2 Q12809 1/20 0.30
NR1H2 P55055 1/20 0.30
BAX Q07812 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29048904 0.85 KIF11 (0.40) KIF11ALDH1A1ALOX15TSHRMEN1
SCHEMBL132913 0.78 LTA4H (0.45) ALDH1A1ALOX15TSHRLTA4HCA5A
SCHEMBL30883096 0.78 LTA4H (0.45) ALDH1A1ALOX15TSHRLTA4HCA5A
SCHEMBL29259913 0.78 PDK1 (0.35) ALDH1A1TSHRLTA4HCA5ACA5B
SCHEMBL5080405 0.78 CA4 (0.36) ALDH1A1ALOX15TSHRLTA4HMAPK1
SCHEMBL3969286 0.76 KIF11 (0.40) KIF11ALDH1A1ALOX15TSHRMEN1
SCHEMBL28831578 0.75 LTA4H (0.43) ALDH1A1ALOX15TSHRLTA4HCA5A
SCHEMBL8978293 0.75 LTA4H (0.43) ALDH1A1ALOX15TSHRLTA4HCA5A
SCHEMBL28345841 0.75 LTA4H (0.43) ALDH1A1ALOX15TSHRLTA4HCA5A
Hydrochloric Acid SCHEMBL9814237 0.75 LTA4H (0.43) ALDH1A1ALOX15TSHRLTA4HCA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110337456-A Resin composition for epoxy acrylic refractive optical lens and preparation method thereof 可奥熙搜路司有限公司 2019-10-15 CN claimed
CN-110337456-A Resin composition for epoxy acrylic refractive optical lens and preparation method thereof 可奥熙搜路司有限公司 2019-10-15 CN disclosed