SCHEMBL29048976

SCHEMBL29048976

Cc1cnn(C2CCCO2)c1B1OC(C)(C)C(C)(C)O1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
POLB P06746 2/20 0.43
LMNA P02545 1/20 0.43
CYP4F2 P78329 2/20 0.37
CYP4A11 Q02928 2/20 0.37
GAA P10253 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15388527 0.96 CYP4F2 (0.41) ALDH1A1POLBLMNACYP4F2CYP4A11
SCHEMBL26296337 0.83 CYP4F2 (0.39) ALDH1A1POLBLMNACYP4F2CYP4A11
SCHEMBL26986555 0.82 ALDH1A1 (0.39) ALDH1A1POLBLMNACYP4F2CYP4A11
SCHEMBL3401227 0.81 ALDH1A1 (0.39) ALDH1A1POLBLMNACYP4F2CYP4A11
SCHEMBL31155932 0.80 ALOX15 (0.39) ALDH1A1GAAMEN1KMT2A
SCHEMBL19277096 0.80 ALDH1A1 (0.37) ALDH1A1POLBLMNACYP4F2CYP4A11
SCHEMBL19523845 0.79 CYP4F2 (0.39) ALDH1A1POLBLMNACYP4F2CYP4A11
SCHEMBL28388363 0.76 SRC (0.34)
SCHEMBL25795327 0.76 RXRA (0.40) ALDH1A1POLBLMNACYP4F2CYP4A11
SCHEMBL38657973 0.76 KDM4C (0.39) ALDH1A1POLBLMNACYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115925688-B Heterocyclic compound, and pharmaceutical composition and application thereof 英矽智能科技(上海)有限公司 2023-05-26 CN disclosed