Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268381 | 0.76 | CRBN (0.70) | FFAR1GLACRBNDDB1GAA | |
| SCHEMBL28663778 | 0.76 | CRBN (0.50) | GLACRBNDDB1L3MBTL1MAPT | |
| SCHEMBL4942730 | 0.74 | GPR39 (0.46) | GLACRBNDDB1L3MBTL1NPC1 | |
| SCHEMBL30569683 | 0.73 | CMA1 (0.44) | CMA1TAAR1ROCK2NPC1RAB9A | |
| SCHEMBL29158181 | 0.73 | FFAR1 (0.65) | FFAR1GLACRBNDDB1CMA1 | |
| SCHEMBL29049309 | 0.73 | FFAR1 (0.65) | FFAR1GLACRBNDDB1CMA1 | |
| Bicarbonate SCHEMBL29264497 | 0.72 | CRBN (0.64) | FFAR1GLACRBNDDB1L3MBTL1 | |
| SCHEMBL29049422 | 0.72 | FFAR1 (0.56) | FFAR1GLACRBNDDB1CMA1 | |
| SCHEMBL30526504 | 0.72 | FFAR1 (0.56) | FFAR1GLACRBNDDB1CMA1 | |
| SCHEMBL2672584 | 0.71 | HSD17B10 (0.47) | MAPK1RXFP1L3MBTL1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554079-B | Histone deacetylase inhibitor and application thereof | 南京市鸿舜医药科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116554079-A | Histone deacetylase inhibitor and application thereof | 南京市鸿舜医药科技有限公司 | 2023-08-08 | — | — | CN | disclosed |