SCHEMBL30569683

SCHEMBL30569683

O=C1C(Cc2ccccc2Cl)CNCC1Cc1ccccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 1/20 0.44
SLC6A4 P31645 4/20 0.41
SLC6A2 P23975 3/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
SLC6A3 Q01959 1/20 0.41
ROCK2 O75116 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
PNMT P11086 1/20 0.38
IDO1 P14902 1/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CES2 O00748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13719433 0.81 CMA1 (0.41) CMA1SLC6A4SLC6A2CYP1A2CYP3A4
SCHEMBL30569684 0.79 CYP27A1 (0.41) SLC6A4SLC6A2TAAR1IDO1
SCHEMBL23830937 0.78 SLC6A4 (0.45) SLC6A4SLC6A2CYP1A2CYP3A4CYP2D6
SCHEMBL30569688 0.78 SLC6A4 (0.40) SLC6A4HTR6
SCHEMBL31518767 0.77 KDM4E (0.42) CMA1ROCK2MEN1KMT2ASMN1; SMN2
SCHEMBL29049348 0.73 FFAR1 (0.46) CMA1ROCK2NPC1RAB9ATAAR1
SCHEMBL31518772 0.73 SLC6A2 (0.41) CMA1SLC6A4SLC6A2SLC6A3ROCK2
SCHEMBL29718876 0.71 PTGS1 (0.42) CMA1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL30569687 0.71 PYCR1 (0.38) CMA1SLC6A4NPC1IDO1
SCHEMBL30569682 0.71 NOS3 (0.38) CMA1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115232068-B Compound and preparation method and application thereof 北京中医药大学 2023-09-08 CN disclosed