Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525574 | 1.00 | P2RX7 (0.47) | P2RX7EGLN1CYP2C8EGLN2EGLN3 | |
| SCHEMBL30525571 | 0.84 | HPGDS (0.48) | P2RX7ALDH1A1MAPTMEN1MITF | |
| SCHEMBL29049509 | 0.84 | HPGDS (0.48) | P2RX7ALDH1A1MAPTMEN1MITF | |
| SCHEMBL29694398 | 0.83 | DHODH (0.45) | EGLN1CYP2C8EGLN2EGLN3ALDH1A1 | |
| SCHEMBL932031 | 0.83 | DHODH (0.45) | EGLN1CYP2C8EGLN2EGLN3ALDH1A1 | |
| SCHEMBL3406643 | 0.82 | EGLN1 (0.63) | EGLN1CYP2C8EGLN2EGLN3ALDH1A1 | |
| SCHEMBL16386456 | 0.82 | EGLN1 (0.36) | P2RX7EGLN1CYP2C8EGLN2EGLN3 | |
| SCHEMBL2589430 | 0.82 | EGLN1 (0.41) | EGLN1CYP2C8EGLN2EGLN3ALDH1A1 | |
| SCHEMBL3402667 | 0.81 | EGLN1 (0.53) | EGLN1CYP2C8EGLN2EGLN3KCNH2 | |
| SCHEMBL3411763 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514769-B | 4-hydroxy pyrimidine-5-formylhydrazone derivative, preparation method, pharmaceutical composition and application | 中国药科大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-116514769-A | 4-hydroxy pyrimidine-5-formylhydrazone derivative, preparation method, pharmaceutical composition and application | 中国药科大学 | 2023-08-01 | — | — | CN | disclosed |