Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PER2 | O15055 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22541554 | 0.89 | PER2 (0.36) | PER2 | |
| SCHEMBL16230708 | 0.89 | PER2 (0.36) | PER2 | |
| SCHEMBL21339377 | 0.81 | CYP2D6 (0.32) | — | |
| SCHEMBL16421826 | 0.75 | BRD4 (0.37) | TDP1ALDH1A1MAPT | |
| SCHEMBL21339378 | 0.75 | PER2 (0.35) | MAPTPER2 | |
| SCHEMBL19565546 | 0.75 | PER2 (0.35) | MAPTPER2 | |
| SCHEMBL9549307 | 0.73 | TDP1 (0.36) | TDP1ALDH1A1MAPT | |
| SCHEMBL12052851 | 0.73 | ALDH1A1 (0.36) | TDP1ALDH1A1MAPT | |
| SCHEMBL10491078 | 0.73 | P2RX7 (0.37) | TDP1ALDH1A1PER2 | |
| SCHEMBL18383589 | 0.73 | BRD4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116171280-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-05-26 | — | — | CN | disclosed |