Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30768404 | 1.00 | ACE (0.54) | ACEP2RX7 | |
| SCHEMBL11586091 | 0.81 | P2RX7 (0.45) | ACEP2RX7 | |
| Lithium Ion SCHEMBL31694855 | 0.79 | P2RX7 (0.44) | ACEP2RX7 | |
| SCHEMBL15123049 | 0.79 | ACE (0.65) | ACEP2RX7 | |
| Lithium Ion SCHEMBL31694795 | 0.79 | P2RX7 (0.44) | ACEP2RX7 | |
| SCHEMBL31694805 | 0.78 | ACE (0.63) | ACEP2RX7 | |
| SCHEMBL1636712 | 0.78 | BRD4 (0.49) | ACEP2RX7 | |
| SCHEMBL8231727 | 0.78 | BRD4 (0.49) | ACEP2RX7 | |
| SCHEMBL29050322 | 0.78 | ACE (0.63) | ACEP2RX7 | |
| SCHEMBL1637684 | 0.76 | MAPT (0.49) | ACEP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4631573-A2 | TEAD INHIBITORS | Orion Corporation (FI) | 2025-10-15 | — | — | EP | disclosed |
| US-7932282-B2 | Imidazolidine carboxamide derivatives as P2X7 modulators | GLAXO GROUP LIMITED (GB) | 2011-04-26 | — | — | US | disclosed |
| US-20100075968-A1 | Imidazolidine Carboxamide Derivatives as P2X7 Modulators | GLAXO GROUP LIMITED (GB) | 2010-03-25 | — | — | US | disclosed |
| CN-101679291-A | Imidazolidine carboxamide derivatives as P2X7 modulators | GLAXO GROUP LTD | 2010-03-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075968-A1 | Imidazolidine Carboxamide Derivatives as P2X7 Modulators | P2RX3, P2RX7, P2RX5 | ACE 2499/4885P2RX7 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.