SCHEMBL30768404

SCHEMBL30768404

CN1C[C@@H](C(=O)O)N(C)C1=O

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACE P12821 4/20 0.54
P2RX7 Q99572 16/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1636773 1.00 ACE (0.54) ACEP2RX7
SCHEMBL11586091 0.81 P2RX7 (0.45) ACEP2RX7
Lithium Ion SCHEMBL31694855 0.79 P2RX7 (0.44) ACEP2RX7
SCHEMBL15123049 0.79 ACE (0.65) ACEP2RX7
Lithium Ion SCHEMBL31694795 0.79 P2RX7 (0.44) ACEP2RX7
SCHEMBL31694805 0.78 ACE (0.63) ACEP2RX7
SCHEMBL1636712 0.78 BRD4 (0.49) ACEP2RX7
SCHEMBL8231727 0.78 BRD4 (0.49) ACEP2RX7
SCHEMBL29050322 0.78 ACE (0.63) ACEP2RX7
SCHEMBL1637684 0.76 MAPT (0.49) ACEP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4631573-A2 TEAD INHIBITORS Orion Corporation (FI) 2025-10-15 EP disclosed
EP-4323338-B1 TEAD INHIBITORS ORION CORP (FI) 2025-10-08 EP disclosed
CN-117500786-A TEAD inhibitors 奥赖恩公司 2024-02-02 CN disclosed