Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.41 |
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486788 | 0.72 | POLB (0.42) | POLBCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL24185394 | 0.72 | POLB (0.46) | POLBCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL27585155 | 0.72 | CYP3A4 (0.59) | POLBCHRNB4CHRNA3LMNAL3MBTL1 | |
| SCHEMBL15836997 | 0.72 | NOTUM (0.40) | POLBOXTRAVPR1AMAPT | |
| SCHEMBL27529815 | 0.71 | POLB (0.41) | POLBCHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL2860419 | 0.70 | POLB (0.40) | POLBCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL21568776 | 0.69 | POLB (0.52) | POLBCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL2450998 | 0.69 | PTGS2 (0.40) | POLBCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL18098652 | 0.69 | KDM4E (0.56) | POLBOXTRAVPR1ALMNAL3MBTL1 | |
| SCHEMBL3577175 | 0.69 | OXTR (0.57) | OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568676-A | IL-17A modulators | 赛诺菲 | 2023-08-08 | — | — | CN | disclosed |
| CN-116547275-A | IL-17A modulators | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |
| EP-4157827-A1 | IL-17A MODULATORS | SANOFI (FR) | 2023-04-05 | — | — | EP | disclosed |