Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29050464 | 0.83 | MEN1 (0.40) | MEN1KMT2ACHRNB2CHRNA4PIK3CD | |
| SCHEMBL16200254 | 0.80 | MEN1 (0.47) | MEN1KMT2ACHRNB2CHRNA4PIK3CD | |
| SCHEMBL30231174 | 0.80 | ATM (0.48) | MEN1KMT2APIK3CDNPC1RAB9A | |
| SCHEMBL29050476 | 0.77 | DRD2 (0.48) | MEN1KMT2ACHRNB2CHRNA4CHRNA3 | |
| SCHEMBL24185712 | 0.75 | SMN1; SMN2 (0.54) | MEN1KMT2ACHRNB2CHRNA4PIK3CD | |
| SCHEMBL30231061 | 0.74 | GRIN2B (0.41) | KDM4EALDH1A1HPGDHTT | |
| SCHEMBL16861812 | 0.73 | PIK3CD (0.44) | PIK3CD | |
| SCHEMBL22230040 | 0.72 | PIK3CD (0.43) | MEN1KMT2ACHRNB2CHRNA4PIK3CD | |
| SCHEMBL22230141 | 0.72 | CHRNB2 (0.40) | MEN1KMT2ACHRNB2CHRNA4PIK3CD | |
| SCHEMBL29050459 | 0.72 | BRD4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568676-A | IL-17A modulators | 赛诺菲 | 2023-08-08 | — | — | CN | disclosed |
| CN-116547275-A | IL-17A modulators | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |
| EP-4157827-A1 | IL-17A MODULATORS | SANOFI (FR) | 2023-04-05 | — | — | EP | disclosed |