Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29050472 | 0.77 | MEN1 (0.47) | CHRNB2CHRNA4MEN1KMT2ACHRNB4 | |
| SCHEMBL30558860 | 0.75 | DRD2 (0.52) | DRD2DRD4DRD3BRD4 | |
| SCHEMBL29050464 | 0.74 | MEN1 (0.40) | CHRNB2CHRNA4MEN1KMT2A | |
| SCHEMBL30231061 | 0.66 | GRIN2B (0.41) | — | |
| SCHEMBL8488616 | 0.66 | CHRNB2 (0.46) | CHRNB2CHRNA4MEN1KMT2ACHRNA3 | |
| SCHEMBL16200254 | 0.65 | MEN1 (0.47) | CHRNB2CHRNA4MEN1KMT2ACHRNB4 | |
| SCHEMBL1662273 | 0.63 | PIK3CD (0.73) | CHRNB2CHRNA4MEN1KMT2ACHRNA3 | |
| SCHEMBL24185712 | 0.63 | SMN1; SMN2 (0.54) | CHRNB2CHRNA4MEN1KMT2ACHRNB4 | |
| SCHEMBL21263051 | 0.63 | DRD2 (0.36) | DRD2DRD4DRD3BRD4 | |
| SCHEMBL8208017 | 0.62 | SLC6A2 (0.52) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568676-A | IL-17A modulators | 赛诺菲 | 2023-08-08 | — | — | CN | disclosed |
| CN-116547275-A | IL-17A modulators | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |