Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376774 | 0.89 | MAPT (0.60) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8220273 | 0.83 | NPC1 (0.60) | NPC1RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL15823215 | 0.83 | DHODH (0.73) | NPC1RAB9AALDH1A1SMN1; SMN2SLC16A3 | |
| SCHEMBL29050680 | 0.83 | RAB9A (0.64) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL11079536 | 0.81 | PDCD1 (0.72) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28431287 | 0.80 | RAB9A (0.60) | NPC1RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL14856050 | 0.80 | DHODH (0.69) | NPC1RAB9AALDH1A1SMN1; SMN2SLC16A3 | |
| SCHEMBL14855972 | 0.80 | HPGD (0.68) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL9339256 | 0.80 | TSHR (0.76) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL13623623 | 0.79 | ALDH1A1 (0.64) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589406-A | Preparation method of polysubstituted acridine derivative | 深圳职业技术学院 | 2023-08-15 | — | — | CN | disclosed |