Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | UGCG | Q16739 | 5/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 5/20 | 0.41 |
| ▸ | GBA1 | P04062 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GYPA | P02724 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LCT | P09848 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30052193 | 1.00 | PDE4D (0.44) | PDE4DUGCGGBA2GBA1EPHX2 | |
| SCHEMBL30051811 | 1.00 | PDE4D (0.44) | PDE4DUGCGGBA2GBA1EPHX2 | |
| SCHEMBL14303008 | 0.80 | TSHR (0.47) | PDE4DUGCGGBA2GBA1EPHX2 | |
| SCHEMBL30053595 | 0.77 | PDE4D (0.36) | PDE4DUGCGGBA2GBA1EPHX2 | |
| SCHEMBL30890189 | 0.77 | PDE4D (0.36) | PDE4DUGCGGBA2GBA1EPHX2 | |
| SCHEMBL3316782 | 0.76 | LTA4H (0.48) | PDE4DALDH1A1AGTR2 | |
| SCHEMBL3316138 | 0.75 | LTA4H (0.47) | ALDH1A1 | |
| SCHEMBL3318052 | 0.75 | LTA4H (0.47) | ALDH1A1 | |
| SCHEMBL3316807 | 0.75 | ALDH1A1 (0.36) | PDE4DEPHX2TSHRALDH1A1AGTR2 | |
| SCHEMBL3318807 | 0.74 | RAB9A (0.41) | ALDH1A1TDP1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340441-A | Synthesis method of chiral cyclobutanol compound, chiral cyclobutanol and application | 复旦大学 | 2022-11-15 | — | — | CN | disclosed |