Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21799423 | 0.88 | SCN9A (0.41) | IRAK4SCN9ASMN1; SMN2DGAT1CCNA2 | |
| SCHEMBL29050891 | 0.85 | NPC1 (0.46) | SMN1; SMN2DGAT1NPC1RAB9AMEN1 | |
| SCHEMBL21799374 | 0.78 | SCN9A (0.33) | IRAK4SCN9ADGAT1CYP2A6 | |
| SCHEMBL21799410 | 0.77 | IRAK4 (0.43) | IRAK4SCN9ASMN1; SMN2DGAT1CCNA2 | |
| SCHEMBL21799433 | 0.73 | IRAK4 (0.46) | IRAK4SCN9ASMN1; SMN2DGAT1CCNA2 | |
| SCHEMBL21799424 | 0.73 | SGMS2 (0.47) | IRAK4KMT2AALDH1A1 | |
| SCHEMBL12800042 | 0.72 | IRAK4 (0.50) | IRAK4CCNA2CDK2CCNA1MEN1 | |
| SCHEMBL21799422 | 0.72 | IRAK4 (0.50) | IRAK4SMN1; SMN2CCNA2CDK2CCNA1 | |
| SCHEMBL21799421 | 0.72 | DGAT1 (0.37) | IRAK4DGAT1NPC1RAB9AMEN1 | |
| SCHEMBL23234395 | 0.70 | IRAK4 (0.43) | IRAK4SCN9ASMN1; SMN2DGAT1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612295-B | Pyrazole-3-carboxylic acid amide derivative and pest control agent | 组合化学工业株式会社 | 2023-07-14 | — | — | CN | disclosed |