Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2942902 | 0.99 | ROCK2 (0.37) | RAB9ANPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL2911427 | 0.90 | LMNA (0.40) | RAB9ANPC1ALDH1A1KDM4ELMNA | |
| SCHEMBL2905201 | 0.89 | LMNA (0.36) | RAB9ANPC1ALDH1A1KDM4ELMNA | |
| SCHEMBL2912995 | 0.89 | SMN1; SMN2 (0.39) | RAB9ANPC1ALDH1A1KDM4ELMNA | |
| SCHEMBL2913207 | 0.89 | RAB9A (0.51) | RAB9ANPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL2905197 | 0.88 | KDM4E (0.35) | RAB9ANPC1ALDH1A1KDM4ELMNA | |
| SCHEMBL2909184 | 0.87 | RAB9A (0.41) | RAB9ANPC1ALDH1A1KDM4ELMNA | |
| SCHEMBL2913347 | 0.87 | RAB9A (0.42) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL4092709 | 0.85 | TP53 (0.31) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL2938828 | 0.83 | RAB9A (0.42) | RAB9ANPC1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481679-B1 | ANTIDEPRESSANT | TAKEDA PHARMACEUTICAL (JP) | 2010-08-25 | — | — | EP | disclosed |