Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.38 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.38 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18194347 | 0.80 | KMT2A (0.39) | KDRMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL22587402 | 0.77 | GAA (0.48) | MEN1MAPTMAPK1KMT2ANFKB1 | |
| SCHEMBL18194324 | 0.75 | MAPT (0.45) | MAPTMAPK1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL30426632 | 0.74 | TDP1 (0.57) | KDRMEN1MAPTMAPK1KMT2A | |
| SCHEMBL18194325 | 0.73 | PIP4K2C (0.41) | MAPTEGFRERBB2ERBB3ERBB4 | |
| SCHEMBL24175602 | 0.73 | PAK4 (0.52) | MEN1KMT2A | |
| SCHEMBL30960995 | 0.73 | NPY5R (0.66) | MEN1MAPTMAPK1KMT2ANFKB1 | |
| SCHEMBL2257238 | 0.73 | NPY5R (0.66) | MEN1MAPTMAPK1KMT2ANFKB1 | |
| SCHEMBL1716246 | 0.72 | PRMT5 (0.33) | KDRSMN1; SMN2 | |
| SCHEMBL20273937 | 0.70 | IRAK4 (0.46) | KMT2ANFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178374-B | Small-conductance calcium-activated potassium ion channel agonist, synthesis and application thereof | 河北医科大学 | 2024-10-08 | — | — | CN | disclosed |
| CN-116178374-A | Small-conductance calcium-activated potassium ion channel agonist, synthesis and application thereof | 河北医科大学 | 2023-05-30 | — | — | CN | disclosed |