SCHEMBL2905321

SCHEMBL2905321

O=C1CC=Cc2[nH]c3ccccc3c21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.42
ALDH1A1 P00352 6/20 0.42
LMNA P02545 2/20 0.42
HPGD P15428 2/20 0.42
GAA P10253 2/20 0.42
GLA P06280 1/20 0.42
HTT P42858 1/20 0.42
ATM Q13315 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
HSD17B10 Q99714 3/20 0.40
CYP1A2 P05177 3/20 0.40
PARP1 P09874 2/20 0.40
GPR3 P46089 2/20 0.40
TNKS2 Q9H2K2 2/20 0.40
TNKS O95271 1/20 0.40
BLM P54132 1/20 0.40
PMP22 Q01453 1/20 0.40
PARP15 Q460N3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10973766 0.90 KDM4E (0.48) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL989527 0.76 MEN1 (0.35) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL10759873 0.74 CDC25A (0.50) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL5891207 0.74 HSD17B10 (0.44) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL20476303 0.72 KDM4E (0.46) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL28841465 0.71 CCR6 (0.47) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL4287798 0.69 KDM4E (0.50) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL30451928 0.69 KDM4E (0.50) KDM4EALDH1A1LMNAHPGDGAA
SCHEMBL29407440 0.67 ALDH1A1 (0.33) KDM4EALDH1A1LMNAHPGDGLA
SCHEMBL31027151 0.67 DYRK1A (0.58) KDM4EALDH1A1LMNAHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1999166-B2 MODIFIED WAXES, A PROCESS FOR THEIR PREPARATION, AND THEIR USE CLARIANT INT LTD (CH) 2016-09-21 EP claimed
US-8765848-B2 Modified waxes, a process for their preparation, and their use CLARIANT FINANCE (BVI) LIMITED (VG) 2014-07-01 US claimed
US-20100286319-A1 Modified Waxes, a Process for Their Preparation, and Their Use CLARIANT FINANCE (BVI) LIMITED (VG) 2010-11-11 US claimed
EP-1999166-B1 MODIFIED WAXES, A PROCESS FOR THEIR PREPARATION, AND THEIR USE CLARIANT FINANCE BVI LTD (VG) 2010-05-19 EP claimed
EP-1999166-B2 MODIFIED WAXES, A PROCESS FOR THEIR PREPARATION, AND THEIR USE CLARIANT INT LTD (CH) 2016-09-21 EP disclosed
US-8765848-B2 Modified waxes, a process for their preparation, and their use CLARIANT FINANCE (BVI) LIMITED (VG) 2014-07-01 US disclosed
US-20100286319-A1 Modified Waxes, a Process for Their Preparation, and Their Use CLARIANT FINANCE (BVI) LIMITED (VG) 2010-11-11 US disclosed
EP-1999166-B1 MODIFIED WAXES, A PROCESS FOR THEIR PREPARATION, AND THEIR USE CLARIANT FINANCE BVI LTD (VG) 2010-05-19 EP disclosed