Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.55 |
| ▸ | PTPRC | P08575 | 1/20 | 0.55 |
| ▸ | PTPRF | P10586 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3606787 | 0.91 | MEN1 (0.60) | HTTTP53PTPN1ALDH1A1KDM4E | |
| SCHEMBL5918953 | 0.89 | THRB (0.66) | HTTTP53PTPN1ALDH1A1KDM4E | |
| SCHEMBL5919026 | 0.89 | PRKCZ (0.62) | HTTTP53PTPN1ALDH1A1KDM4E | |
| SCHEMBL2897094 | 0.88 | POLB (0.74) | HTTPTPN1ALDH1A1KDM4EPOLB | |
| SCHEMBL8289507 | 0.87 | PTPN1 (0.69) | HTTTP53PTPN1ALDH1A1KDM4E | |
| SCHEMBL23579845 | 0.83 | POLB (0.72) | HTTPTPN1ALDH1A1KDM4EPOLB | |
| SCHEMBL5919265 | 0.81 | POLB (0.62) | HTTPTPN1ALDH1A1KDM4EPOLB | |
| SCHEMBL3629109 | 0.81 | MAPT (0.72) | HTTTP53PTPN1ALDH1A1KDM4E | |
| SCHEMBL3620747 | 0.81 | THRB (0.80) | HTTTP53PTPN1ALDH1A1KDM4E | |
| SCHEMBL3627300 | 0.81 | MAPT (0.72) | HTTTP53PTPN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879899-B1 | THIENOPYRIDINE DERIVATIVES AS POTASSIUM CHANNEL INHIBITORS | XENTION LTD (GB) | 2010-08-04 | — | — | EP | disclosed |