Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13827672 | 0.83 | POLB (0.53) | POLBHSD17B10KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12158537 | 0.82 | HSD17B10 (0.52) | POLBHSD17B10KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15113629 | 0.82 | HSD17B10 (0.52) | POLBHSD17B10KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28358827 | 0.81 | CCR2 (0.46) | KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7825419 | 0.81 | HSD17B10 (0.44) | POLBHSD17B10KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28391915 | 0.81 | PARP1 (0.39) | POLBHSD17B10KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2760258 | 0.78 | FKBP1A (0.55) | HSD17B10 | |
| SCHEMBL5411479 | 0.77 | HSD17B10 (0.57) | POLBHSD17B10KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5411482 | 0.77 | HSD17B10 (0.57) | POLBHSD17B10KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13819936 | 0.77 | HSD17B10 (0.57) | POLBHSD17B10KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116615417-A | 1, 4-diheterocycle substituted aromatic ring or aromatic heterocyclic compound and application thereof | 广州必贝特医药股份有限公司 | 2023-08-18 | — | — | CN | disclosed |