Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 3/20 | 0.44 |
| ▸ | REN | P00797 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29055986 | 0.81 | POLB (0.45) | HSD17B10SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL65490 | 0.79 | HSD17B10 (0.63) | HSD17B10RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL77858 | 0.79 | HSD17B10 (0.63) | HSD17B10RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL65491 | 0.79 | HSD17B10 (0.63) | HSD17B10RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL18358031 | 0.78 | HSD17B10 (0.62) | HSD17B10RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5898691 | 0.78 | HSD17B10 (0.62) | HSD17B10RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL222955 | 0.78 | HSD17B10 (0.62) | HSD17B10RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL23394426 | 0.76 | ACE (0.51) | HSD17B10ACERENRAB9A | |
| SCHEMBL85536 | 0.75 | HSD17B10 (0.69) | HSD17B10RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL67045 | 0.75 | HSD17B10 (0.69) | HSD17B10RAB9ASMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |