Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924489 | 0.90 | ABL1 (0.46) | MAPTLMNATP53KDM4EALDH1A1 | |
| SCHEMBL24619425 | 0.90 | ABL1 (0.46) | MAPTLMNATP53KDM4EALDH1A1 | |
| SCHEMBL29924714 | 0.90 | LMNA (0.46) | MAPTLMNATP53THRBRXFP1 | |
| SCHEMBL24619522 | 0.90 | LMNA (0.46) | MAPTLMNATP53THRBRXFP1 | |
| SCHEMBL29924918 | 0.80 | LMNA (0.53) | MAPTLMNATP53THRBRXFP1 | |
| SCHEMBL24619361 | 0.80 | LMNA (0.53) | MAPTLMNATP53THRBRXFP1 | |
| SCHEMBL30537883 | 0.79 | MAPT (0.46) | MAPTLMNATP53KDM4EALDH1A1 | |
| SCHEMBL29924901 | 0.77 | MAPT (0.59) | MAPTLMNATP53KDM4EALDH1A1 | |
| SCHEMBL24740863 | 0.77 | LMNA (0.54) | MAPTLMNATP53THRBRXFP1 | |
| SCHEMBL24619426 | 0.77 | MAPT (0.48) | MAPTLMNATP53THRBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635028-A | Modulators of c-MYC mRNA translation and their use in the treatment of cancer | 艾尼莫生物科技公司 | 2023-08-22 | — | — | CN | disclosed |