Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2303835 | 0.89 | ADRA2A (0.70) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| Hydrochloric Acid SCHEMBL3430810 | 0.87 | MAPT (0.71) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| Hydrochloric Acid SCHEMBL19025644 | 0.87 | ADRA2A (0.67) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| Bromide SCHEMBL21643594 | 0.87 | ADRA2A (0.67) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| Iodide SCHEMBL11128066 | 0.87 | ADRA2A (0.67) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| Propionic Acid SCHEMBL23044698 | 0.83 | ADRA2A (0.61) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| Acetylcholine SCHEMBL28671890 | 0.82 | CHRM1 (0.79) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| Propionic Acid SCHEMBL19617436 | 0.82 | ADRA2A (0.59) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| Choline SCHEMBL31574099 | 0.82 | ADRA2A (0.59) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| SCHEMBL13988530 | 0.79 | NAAA (0.57) | ADRA2AADRA1AMAPTBLMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210023009-A1 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | BEN GURION UNIV OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2021-01-28 | — | — | US | disclosed |
| US-10842747-B2 | Nano-sized particles comprising multi-headed amphiphiles for targeted drug delivery | Ben-Gurion University of Negev R & D (IL) | 2020-11-24 | — | — | US | disclosed |
| EP-3539535-A1 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | Ben-Gurion University of The Negev Research and Development Authority (IL) | 2019-09-18 | — | — | EP | disclosed |
| EP-2427175-B1 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | BEN GURION UNIV OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2018-08-29 | — | — | EP | disclosed |
| US-20170367980-A1 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | C/O BEN-GURION UNIV OF THE NEGEV R & D (IL) | 2017-12-28 | — | — | US | disclosed |
| US-9642803-B2 | Nano-sized particles comprising multi-headed amphiphiles for targeted drug delivery | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2017-05-09 | — | — | US | disclosed |
| US-20120164072-A1 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2012-06-28 | — | — | US | disclosed |
| EP-2427175-A2 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | Ben-gurion University Of The Negev Research And Development Authority (IL) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128504-A2 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170367980-A1 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | TSPO, ANXA6, ANXA11 | ADRA2A 3824/4885ADRA1A 2705/4885MAPT 1081/4885 |
| US-20120164072-A1 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | TSPO, ANXA6, ANXA11 | ADRA2A 3824/4885ADRA1A 2705/4885MAPT 1081/4885 |
| US-20210023009-A1 | NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY | TSPO, ANXA6, ANXA11 | ADRA2A 3824/4885ADRA1A 2705/4885MAPT 1081/4885 |
| US-10842747-B2 | Nano-sized particles comprising multi-headed amphiphiles for targeted drug delivery | TSPO, ANXA6, ANXA11 | ADRA2A 3824/4885ADRA1A 2705/4885MAPT 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.