Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.39 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24073703 | 0.91 | KDM4E (0.43) | APPKDM4EGAANAMPTL3MBTL1 | |
| SCHEMBL30339229 | 0.76 | L3MBTL1 (0.53) | APPKDM4EGAANAMPTL3MBTL1 | |
| SCHEMBL24072432 | 0.76 | L3MBTL1 (0.53) | APPKDM4EGAANAMPTL3MBTL1 | |
| SCHEMBL14755842 | 0.75 | SRD5A1 (0.47) | KDM4ENAMPTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL27135609 | 0.73 | MAOB (0.37) | KDM4EGAAL3MBTL1ALDH1A1POLB | |
| SCHEMBL21787245 | 0.73 | HDAC1 (0.39) | — | |
| SCHEMBL10029414 | 0.72 | L3MBTL1 (0.58) | KDM4EGAAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL16260995 | 0.72 | TMEM97 (0.49) | KDM4EGAANAMPTKMT2AALDH1A1 | |
| SCHEMBL24172856 | 0.72 | HPGD (0.40) | KDM4EGAAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL27462106 | 0.72 | GAA (0.55) | KDM4EGAAKMT2ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472292-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |