Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16260992 | 0.90 | LMNA (0.56) | TMEM97SIGMAR1LMNAALDH1A1SLC22A2 | |
| SCHEMBL16261004 | 0.88 | ALDH1A1 (0.41) | TMEM97SIGMAR1LMNAALDH1A1SLC22A2 | |
| SCHEMBL15836551 | 0.87 | KMT2A (0.51) | TMEM97SIGMAR1LMNAALDH1A1SLC22A2 | |
| SCHEMBL16261002 | 0.84 | KMT2A (0.50) | TMEM97SIGMAR1LMNAALDH1A1SLC22A2 | |
| SCHEMBL16260998 | 0.83 | KMT2A (0.43) | TMEM97SIGMAR1LMNAALDH1A1SLC22A2 | |
| SCHEMBL17547279 | 0.82 | LMNA (0.47) | TMEM97SIGMAR1LMNAALDH1A1SLC22A2 | |
| SCHEMBL15836548 | 0.79 | ALDH1A1 (0.61) | LMNAALDH1A1SLC22A2SLC22A1TSHR | |
| SCHEMBL16260993 | 0.79 | KMT2A (0.46) | TMEM97SIGMAR1LMNAALDH1A1SLC22A2 | |
| SCHEMBL17547235 | 0.78 | KMT2A (0.49) | TMEM97SIGMAR1LMNAALDH1A1SLC22A2 | |
| SCHEMBL11919098 | 0.78 | LMNA (0.58) | TMEM97SIGMAR1LMNAALDH1A1SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200174008-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | WATERS TECHNOLOGIES CORPORATION | 2020-06-04 | — | — | US | disclosed |
| US-10436790-B2 | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals | WATERS TECHNOLOGIES CORPORATION (US) | 2019-10-08 | — | — | US | disclosed |
| US-20140350263-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | WATERS TECHNOLOGIES CORPORATION (US) | 2014-11-27 | — | — | US | disclosed |
| US-20140350263-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | WATERS TECHNOLOGIES CORPORATION (US) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350263-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | FUT5, FUT6, CSGALNACT1 | TMEM97 4459/4885SIGMAR1 4664/4885LMNA 1566/4885 |
| US-20200174008-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | FUT5, FUT6, CSGALNACT1 | TMEM97 4459/4885SIGMAR1 4664/4885LMNA 1566/4885 |
| US-10436790-B2 | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals | FUT5, FUT6, CSGALNACT1 | TMEM97 4758/4885SIGMAR1 4557/4885LMNA 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.