Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24072432 | 1.00 | L3MBTL1 (0.53) | L3MBTL1KDM4EKMT2AGAAAPP | |
| SCHEMBL24073741 | 0.88 | SIRT5 (0.54) | L3MBTL1KDM4EKMT2AGAAALDH1A1 | |
| SCHEMBL12062843 | 0.87 | L3MBTL1 (0.55) | L3MBTL1KDM4EKMT2AGAAALDH1A1 | |
| SCHEMBL15495302 | 0.84 | BCL2 (0.46) | L3MBTL1KDM4EKMT2AGAAAPP | |
| SCHEMBL10029414 | 0.83 | L3MBTL1 (0.58) | L3MBTL1KDM4EKMT2AGAAALDH1A1 | |
| SCHEMBL12601200 | 0.79 | POLB (0.53) | L3MBTL1KDM4EKMT2AGAAALDH1A1 | |
| SCHEMBL10789854 | 0.78 | KDM4E (0.62) | L3MBTL1KDM4EKMT2AGAAALDH1A1 | |
| SCHEMBL28898473 | 0.78 | L3MBTL1 (0.55) | L3MBTL1KDM4EKMT2AGAAALDH1A1 | |
| SCHEMBL13918749 | 0.77 | KDM4E (0.70) | L3MBTL1KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL6714816 | 0.77 | NAAA (0.64) | L3MBTL1TDP1THRBSMN1; SMN2NME4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472292-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| EP-4157888-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2023-04-05 | — | — | EP | disclosed |