SCHEMBL29057705

SCHEMBL29057705

CCCC(C)(C)C(C)(C)C(=O)O.[BiH3]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
TSHR P16473 2/20 0.35
ACLY P53396 1/20 0.34
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
ACACB O00763 1/20 0.33
ACACA Q13085 1/20 0.33
FFAR3 O14843 2/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ELANE P08246 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3724147 0.97 ALDH1A1 (0.36) ALDH1A1TSHRACLYLMNAHSD17B10
SCHEMBL29275052 0.86 ACLY (0.36) ALDH1A1TSHRACLYHSD17B10ACACB
SCHEMBL1114580 0.83 ACLY (0.38) ALDH1A1TSHRACLYHSD17B10ACACB
SCHEMBL28323669 0.81 AKR1B1 (0.41) ALDH1A1TSHRACLYHSD17B10ACACB
SCHEMBL18097881 0.79 CES2 (0.44) ALDH1A1TSHRACLYHSD17B10MEN1
SCHEMBL5970077 0.79 CES2 (0.44) ALDH1A1TSHRACLYHSD17B10MEN1
SCHEMBL7613392 0.79 CES2 (0.44) ALDH1A1TSHRACLYHSD17B10MEN1
SCHEMBL5166994 0.79 CES2 (0.44) ALDH1A1TSHRACLYHSD17B10MEN1
SCHEMBL8976725 0.79 CES2 (0.44) ALDH1A1TSHRACLYHSD17B10MEN1
Ammonia Solution, Strong SCHEMBL28378227 0.79 CES2 (0.39) ALDH1A1TSHRACLYHSD17B10ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116390995-B Compounds, uses and methods of preparation thereof 马夫隆公司 2024-08-20 CN disclosed
CN-116390995-A Compounds, uses and methods of preparation thereof 马夫隆公司 2023-07-04 CN disclosed