Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.36 |
| ▸ | CDK1 | P06493 | 4/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.36 |
| ▸ | KCNJ6 | P48051 | 5/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 5/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 5/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26976603 | 0.87 | HCAR3 (0.35) | KCNJ6KCNJ5KCNJ3PDK1PDK2 | |
| SCHEMBL26976637 | 0.80 | KMT2A (0.36) | — | |
| SCHEMBL14351946 | 0.78 | PDK1 (0.40) | AURKAKCNJ6KCNJ5KCNJ3PDK1 | |
| SCHEMBL30559528 | 0.73 | CDK8 (0.47) | AURKAMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL20489182 | 0.71 | BRD4 (0.45) | F10 | |
| SCHEMBL28311500 | 0.70 | CNR1 (0.33) | AURKACDK1AURKBF10 | |
| SCHEMBL29793860 | 0.66 | F10 (0.55) | KCNJ6KCNJ5KCNJ3F10 | |
| SCHEMBL30559538 | 0.66 | KCNJ6 (0.39) | AURKACDK1AURKBKCNJ6KCNJ5 | |
| SCHEMBL4043341 | 0.64 | KMT2A (0.43) | AURKACDK1AURKBPDK1PDK2 | |
| SCHEMBL27835273 | 0.63 | KCNJ6 (0.36) | KCNJ6KCNJ5KCNJ3MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589425-A | Cathepsin L inhibitors | 百放英库医药科技(北京)有限公司 | 2023-08-15 | — | — | CN | disclosed |