Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29059266 | 0.89 | KMT2A (0.75) | KMT2AMEN1TSHRNPSR1MAPT | |
| SCHEMBL29059296 | 0.87 | MEN1 (0.53) | KMT2AMEN1TSHRALOX5MAPT | |
| SCHEMBL29059360 | 0.79 | MEN1 (0.56) | KMT2AMEN1TSHRNPSR1PTGES | |
| SCHEMBL333735 | 0.78 | KMT2A (0.63) | KMT2AMEN1TSHRNPSR1PTGES | |
| SCHEMBL334043 | 0.77 | PTGES (0.61) | KMT2AMEN1TSHRNPSR1PTGES | |
| SCHEMBL13576495 | 0.77 | KMT2A (0.82) | KMT2AMEN1TSHRNPSR1MAPT | |
| SCHEMBL333454 | 0.77 | MEN1 (0.74) | KMT2AMEN1TSHRNPSR1PTGES | |
| SCHEMBL333699 | 0.77 | MAPT (0.61) | KMT2AMEN1TSHRNPSR1PTGES | |
| SCHEMBL334361 | 0.76 | ALOX5 (0.61) | KMT2AMEN1TSHRNPSR1PTGES | |
| SCHEMBL29059242 | 0.76 | MEN1 (0.63) | KMT2AMEN1TSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396205-B | N-aryl indole derivative and preparation method and application thereof | 沈阳药科大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-116396205-A | N-aryl indole derivative and preparation method and application thereof | 沈阳药科大学 | 2023-07-07 | — | — | CN | disclosed |