Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.34 |
| ▸ | PIM1 | P11309 | 3/20 | 0.34 |
| ▸ | PLK4 | O00444 | 2/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | PRKACA | P17612 | 2/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.34 |
| ▸ | PLK1 | P53350 | 2/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3740674 | 0.81 | PIK3CG (0.36) | PIK3CGDYRK1APIM1CSNK1DGSK3A | |
| SCHEMBL17589770 | 0.72 | CYP11B1 (0.38) | PIK3CGDYRK1APIM1CYP11B2 | |
| SCHEMBL290156 | 0.71 | PIK3CG (0.37) | PIK3CGDYRK1APIM1PLK4DAPK3 | |
| SCHEMBL3717542 | 0.69 | CYP1A2 (0.61) | PIK3CGCDK2GSK3BCDC7 | |
| SCHEMBL289332 | 0.69 | DYRK1A (0.42) | PIK3CGDYRK1APIM1CSNK1DGSK3A | |
| SCHEMBL17589968 | 0.69 | PIK3CG (0.33) | PIK3CGDYRK1APIM1PTGDR2POLQ | |
| SCHEMBL290811 | 0.69 | PAX8 (0.40) | PIK3CGDYRK1APIM1CSNK1DGSK3A | |
| SCHEMBL28481366 | 0.66 | HCAR2 (0.46) | HCAR2 | |
| SCHEMBL16652932 | 0.65 | CHRM4 (0.36) | PIK3CGDYRK1APTGDR2HCRTR1HCRTR2 | |
| SCHEMBL16653318 | 0.65 | PTGDR2 (0.31) | PIK3CGDYRK1ACYP11B2PTGDR2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2427191-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129497-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-11 | — | — | WO | disclosed |