Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LHCGR | P22888 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290594 | 0.81 | PIK3CG (0.35) | PIK3CGDYRK1ACSNK1DRPS6KB1GSK3A | |
| SCHEMBL289332 | 0.76 | DYRK1A (0.42) | PIK3CGDYRK1ACSNK1DRPS6KB1GSK3A | |
| SCHEMBL290811 | 0.70 | PAX8 (0.40) | PIK3CGDYRK1ACSNK1DRPS6KB1GSK3A | |
| SCHEMBL13074537 | 0.70 | DYRK1A (0.41) | PIK3CGDYRK1APIM1POLQABL1 | |
| SCHEMBL17589770 | 0.70 | CYP11B1 (0.38) | PIK3CGDYRK1APIM1CYP3A4 | |
| SCHEMBL16652932 | 0.70 | CHRM4 (0.36) | PIK3CGDYRK1AHCRTR1HCRTR2POLQ | |
| SCHEMBL16653320 | 0.69 | PIK3CG (0.34) | PIK3CGDYRK1AHCRTR1HCRTR2POLQ | |
| SCHEMBL290156 | 0.68 | PIK3CG (0.37) | PIK3CGDYRK1ACSNK1DGSK3AGSK3B | |
| SCHEMBL3744202 | 0.68 | DYRK1A (0.43) | PIK3CGDYRK1APIM1POLQABL1 | |
| SCHEMBL13048243 | 0.67 | DYRK1A (0.41) | PIK3CGDYRK1APOLQABL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9357780-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2016-06-07 | — | — | US | disclosed |
| EP-2427191-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| EP-2614825-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| EP-2604267-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2016-02-03 | — | — | EP | disclosed |
| EP-2604268-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2015-09-16 | — | — | EP | disclosed |
| US-9006446-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-20150045218-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-02-12 | — | — | US | disclosed |
| US-20140348947-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-11-27 | — | — | US | disclosed |
| US-8853246-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-10-07 | — | — | US | disclosed |
| EP-2614825-A1 | Process for the preparation of thiazole derivatives | Dow AgroSciences LLC (US) | 2013-07-17 | — | — | EP | disclosed |
| EP-2614826-A1 | Process for preparation of thiazole derivatives | Dow AgroSciences LLC (US) | 2013-07-17 | — | — | EP | disclosed |
| EP-2604267-A1 | Process for the preparation of thiazole derivatives | Dow AgroSciences LLC (US) | 2013-06-19 | — | — | EP | disclosed |
| EP-2604268-A1 | Process for the preparation of thiazole derivatives | Dow AgroSciences LLC (US) | 2013-06-19 | — | — | EP | disclosed |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-8350044-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PIK3CG 795/4885DYRK1A 3841/4885CSNK1D 2523/4885 |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PIK3CG 795/4885DYRK1A 3841/4885CSNK1D 2523/4885 |
| US-20140348947-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PIK3CG 795/4885DYRK1A 3841/4885CSNK1D 2523/4885 |
| US-20150045218-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PIK3CG 795/4885DYRK1A 3841/4885CSNK1D 2523/4885 |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PIK3CG 795/4885DYRK1A 3841/4885CSNK1D 2523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.