Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25307104 | 0.75 | KDM1A (0.45) | TPSAB1TPSD1TPSG1NAMPTKDM1A | |
| SCHEMBL29260134 | 0.74 | TPSAB1 (0.50) | TPSAB1TPSD1TPSG1NAMPTKDM1A | |
| SCHEMBL25303116 | 0.74 | DPP4 (0.38) | ATMTPSAB1TPSD1TPSG1NAMPT | |
| SCHEMBL23554104 | 0.74 | NAMPT (0.37) | TPSAB1TPSD1TPSG1NAMPTKDM1A | |
| Hydrochloric Acid SCHEMBL25300129 | 0.73 | KDM1A (0.44) | TPSAB1TPSD1TPSG1NAMPTKDM1A | |
| SCHEMBL22355967 | 0.71 | ATM (0.57) | ATMTDP1CYP1A2CHRM4 | |
| SCHEMBL28900933 | 0.70 | ATM (0.39) | ATMTPSAB1TPSD1TPSG1TDP1 | |
| SCHEMBL23019192 | 0.70 | NAMPT (0.45) | TPSAB1TPSD1TPSG1NAMPTKDM1A | |
| SCHEMBL13694472 | 0.69 | NAMPT (0.47) | TPSAB1TPSD1TPSG1NAMPTKDM1A | |
| SCHEMBL29144075 | 0.69 | TPSAB1 (0.44) | ATMTPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444427-A | Diaryl compounds for tubulin-SRC double-target inhibitor | 武汉人福创新药物研发中心有限公司 | 2023-07-18 | — | — | CN | disclosed |