Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25300129 | 0.98 | KDM1A (0.44) | KDM1ANAMPTSMYD3CYP1A2CHRM4 | |
| SCHEMBL23019192 | 0.86 | NAMPT (0.45) | KDM1ANAMPTSMYD3CYP1A2CHRM4 | |
| SCHEMBL3401470 | 0.79 | — | — | |
| SCHEMBL13694472 | 0.77 | NAMPT (0.47) | KDM1ANAMPTSMYD3CYP1A2CHRM4 | |
| SCHEMBL1462662 | 0.75 | CHRNB2 (0.63) | NAMPTSMYD3CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL14211316 | 0.75 | CHRNB2 (0.60) | NAMPTCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL29059752 | 0.75 | ATM (0.44) | KDM1ANAMPTSMYD3CYP1A2CHRM4 | |
| SCHEMBL14115752 | 0.74 | GNAI3 (0.47) | NAMPTTPSAB1TPSD1TPSG1GNAI3 | |
| SCHEMBL3203246 | 0.74 | L3MBTL1 (0.46) | KDM1ANAMPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3203241 | 0.74 | L3MBTL1 (0.46) | KDM1ANAMPTKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250115613-A1 | DIARYL COMPOUND AS TUBULIN/SRC DUAL TARGET INHIBITOR | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2025-04-10 | — | — | US | disclosed |
| EP-4464700-A1 | DIARYL COMPOUND AS TUBULIN/SRC DUAL TARGET INHIBITOR | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023134752-A1 | DIARYL COMPOUND AS TUBULIN/SRC DUAL TARGET INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-07-20 | — | — | WO | disclosed |
| CN-116444427-A | Diaryl compounds for tubulin-SRC double-target inhibitor | 武汉人福创新药物研发中心有限公司 | 2023-07-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115613-A1 | DIARYL COMPOUND AS TUBULIN/SRC DUAL TARGET INHIBITOR | SRC, DSTYK, TUBB1 | KDM1A 1037/4885NAMPT 1219/4885SMYD3 3029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.