SCHEMBL29059758

SCHEMBL29059758

CCCOC(=O)CCc1ccc(Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.56
CYP4F2 P78329 1/20 0.54
CYP4A11 Q02928 1/20 0.54
L3MBTL1 Q9Y468 3/20 0.51
LMNA P02545 1/20 0.51
PLAAT3 P53816 1/20 0.50
PLAAT5 Q96KN8 1/20 0.50
PLAAT2 Q9NWW9 1/20 0.50
PLAAT4 Q9UL19 1/20 0.50
APP P05067 2/20 0.47
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
KMT2A Q03164 1/20 0.47
ATM Q13315 1/20 0.47
SLC5A1 P13866 1/20 0.46
SLC5A2 P31639 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28968060 0.90 TDP1 (0.53) TDP1CYP4F2CYP4A11L3MBTL1LMNA
SCHEMBL95661 0.86 CYP4F2 (0.72) TDP1CYP4F2CYP4A11LMNAPLAAT3
SCHEMBL10840858 0.85 TDP1 (0.58) TDP1CYP4F2CYP4A11L3MBTL1LMNA
SCHEMBL24988200 0.85 CYP4F2 (0.60) TDP1CYP4F2CYP4A11L3MBTL1LMNA
SCHEMBL1587175 0.85 L3MBTL1 (0.71) TDP1CYP4F2CYP4A11L3MBTL1LMNA
SCHEMBL28010049 0.83 TDP1 (0.56) TDP1CYP4F2CYP4A11L3MBTL1LMNA
SCHEMBL28241121 0.83 TDP1 (0.56) TDP1CYP4F2CYP4A11L3MBTL1LMNA
SCHEMBL3851800 0.83 TDP1 (0.82) TDP1CYP4F2CYP4A11L3MBTL1LMNA
SCHEMBL11776327 0.83 TSHR (0.63) L3MBTL1ALDH1A1POLBKMT2AATM
SCHEMBL275760 0.82 F2RL1 (0.58) TDP1CYP4F2CYP4A11L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116640104-B Industrial synthesis method of telithromycin 杭州科耀医药科技有限公司 2024-04-02 CN claimed
CN-116640104-A Industrial synthesis method of telithromycin 杭州科耀医药科技有限公司 2023-08-25 CN claimed
CN-116640104-B Industrial synthesis method of telithromycin 杭州科耀医药科技有限公司 2024-04-02 CN disclosed
CN-116640104-A Industrial synthesis method of telithromycin 杭州科耀医药科技有限公司 2023-08-25 CN disclosed