Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380292 | 0.76 | SRD5A2 (0.44) | ALDH1A1HTTFNTAFNTBMEN1 | |
| SCHEMBL29140107 | 0.76 | MEN1 (0.44) | ALDH1A1HTTPOLBMEN1KMT2A | |
| Benzophenone SCHEMBL4595056 | 0.64 | ALDH1A1 (0.93) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| Benzophenone SCHEMBL4820258 | 0.64 | ALDH1A1 (0.93) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| Benzophenone SCHEMBL4595059 | 0.64 | ALDH1A1 (0.93) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL11267717 | 0.64 | MAPT (0.78) | ALDH1A1HTTPOLBMEN1KMT2A | |
| SCHEMBL15452568 | 0.64 | RXFP1 (0.67) | ALDH1A1HTTFNTAFNTBMEN1 | |
| Benzophenone SCHEMBL29153438 | 0.62 | ALDH1A1 (0.88) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| Benzophenone SCHEMBL27758204 | 0.62 | ALDH1A1 (0.88) | ALDH1A1POLBMEN1KMT2AL3MBTL1 | |
| Benzophenone SCHEMBL6061130 | 0.61 | ALDH1A1 (1.00) | ALDH1A1POLBMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640135-A | Preparation method of 3-carbonyl-2-fluoro substituted indolizine compound | 平顶山学院 | 2023-08-25 | — | — | CN | claimed |
| CN-116640135-A | Preparation method of 3-carbonyl-2-fluoro substituted indolizine compound | 平顶山学院 | 2023-08-25 | — | — | CN | disclosed |