Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Benzophenone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 known ✓ | Q16539 | 1/20 | 0.61 |
| ▸ | PARP1 known ✓ | P09874 | 1/20 | 0.55 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.55 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.93 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | ATM | Q13315 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL4595056 | 1.00 | ALDH1A1 (0.93) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL4595059 | 1.00 | ALDH1A1 (0.93) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL29153438 | 0.97 | ALDH1A1 (0.88) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL27758204 | 0.97 | ALDH1A1 (0.88) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL30536983 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL28491203 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL1074283 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL30537001 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL6061130 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL28180817 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119552422-A | Organic-inorganic composite ultraviolet absorbent, ultraviolet aging resistant polyethylene plate, and preparation method and application thereof | 石家庄铁道大学 | 2025-03-04 | — | — | CN | claimed |
| CN-114773788-B | Photosensitive resin composition based on nano silicone rubber core-shell structure polymer toughened epoxy resin and application of photosensitive resin composition in 3D printing | 泉州师范学院 | 2023-09-19 | — | — | CN | claimed |
| CN-114045020-A | Chopped fiber reinforced photosensitive resin for 3D printing and preparation method thereof | 重庆交通大学绿色航空技术研究院 | 2022-02-15 | — | — | CN | claimed |
| CN-113831461-A | Bismaleimide/acrylic acid liquid crystal photosensitive resin-based composition and application thereof in 405nm3D printing | 泉州师范学院 | 2021-12-24 | — | — | CN | claimed |
| CN-113736217-A | Composition based on liquid crystal epoxy photosensitive resin and application of composition in 355nm3D printing | 泉州师范学院 | 2021-12-03 | — | — | CN | claimed |
| CN-113651920-A | Composition based on acrylic liquid crystal photosensitive resin and application thereof in 405nm 3D printing | 泉州师范学院 | 2021-11-16 | — | — | CN | claimed |
| CN-113444384-A | UV-moisture dual-curing three-proofing paint and preparation method and application thereof | 深圳市希顺有机硅科技有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-109280395-B | Product prepared by photocuring rapid molding process and preparation method thereof | 北京恒创增材制造技术研究院有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-109867915-B | Photosensitive resin composition based on cardanol and application of photosensitive resin composition in 355nm3D printing | 泉州师范学院 | 2021-08-06 | — | — | CN | claimed |
| CN-113105590-A | Photosensitive resin composition for photocuring 3D printing elastomer and preparation method thereof | 泉州师范学院 | 2021-07-13 | — | — | CN | claimed |
| CN-100427461-C | Polymerisable benzophenone photoinitiator and its preparing method | UNIV SHANGHAI JIAOTONG (CN) | 2008-10-22 | — | — | CN | claimed |
| CN-100372875-C | High molecular benzophenone photoinitiator and its prepn process | UNIV SHANGHAI JIAOTONG (CN) | 2008-03-05 | — | — | CN | claimed |
| CN-100372877-C | High molecular type diphenyl ketone light initiator and its preparing method | UNIV SHANGHAI JIAOTONG (CN) | 2008-03-05 | — | — | CN | claimed |
| CN-100360504-C | Sulfur-containing, polymerizable benzophenone photoinitiator and preparation method thereof | UNIV SHANGHAI JIAOTONG (CN) | 2008-01-09 | — | — | CN | claimed |
| CN-1858078-A | High molecular type diphenyl ketone light initiator and its preparing method | UNIV SHANGHAI JIAOTONG (CN) | 2006-11-08 | — | — | CN | claimed |
| CN-1847275-A | High molecular benzophenone photoinitiator and its prepn process | UNIV SHANGHAI JIAOTONG (CN) | 2006-10-18 | — | — | CN | claimed |
| CN-1844087-A | Polymerisable benzophenone photoinitiator and its preparing method | UNIV SHANGHAI JIAOTONG (CN) | 2006-10-11 | — | — | CN | claimed |
| CN-1793119-A | 4,4'-bis[(4-amino) benzenesulfenyl] diphen methylone and preparation process thereof | UNIV SHANGHAI JIAOTONG (CN) | 2006-06-28 | — | — | CN | claimed |
| CN-1789245-A | Sulfur-containing, polymerizable benzophenone photoinitiator and preparation method thereof | UNIV SHANGHAI JIAOTONG (CN) | 2006-06-21 | — | — | CN | claimed |
| CN-1727335-A | Photoinitiator of benzophenone containing N-phenyl maleimide base group, and preparation method | UNIV SHANGHAI JIAOTONG (CN) | 2006-02-01 | — | — | CN | claimed |