Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 10/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.47 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.47 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 7/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | BHMT | Q93088 | 1/20 | 0.42 |
| ▸ | GCLC | P48506 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL5868317 | 0.89 | PMP22 (0.50) | GRIK1GRIA4GRIK3GRIK5SLC1A3 | |
| Aspartic Acid SCHEMBL5868261 | 0.89 | PMP22 (0.50) | GRIK1GRIA4GRIK3GRIK5SLC1A3 | |
| Aspartic Acid SCHEMBL8888023 | 0.89 | GRIK1 (0.48) | GRIK1GRIA4GRIK3GRIK5SLC1A3 | |
| Aspartic Acid SCHEMBL8888026 | 0.89 | GRIK1 (0.48) | GRIK1GRIA4GRIK3GRIK5SLC1A3 | |
| Aspartic Acid SCHEMBL28252064 | 0.84 | GRIK1 (0.45) | GRIK1GRIA4GRIK3GRIK5SLC1A3 | |
| Aspartic Acid SCHEMBL7782858 | 0.84 | GRIK1 (0.54) | GRIK1GRIA4GRIK3GRIK5SLC1A3 | |
| Aspartic Acid SCHEMBL135731 | 0.84 | GRIK1 (0.57) | GRIK1GRIA4GRIK3GRIK5SLC1A3 | |
| Aspartic Acid SCHEMBL11269603 | 0.84 | GRIK1 (0.54) | GRIK1GRIA4GRIK3GRIK5SLC1A3 | |
| Aspartic Acid SCHEMBL28302585 | 0.84 | SLC7A5 (0.52) | GRIK1GRIA4GRIK3GRIK5SLC1A3 | |
| Aspartic Acid SCHEMBL7781260 | 0.84 | GRIK1 (0.57) | GRIK1GRIA4GRIK3GRIK5SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670113-A | Compositions containing dialkylamino acid ester salts | 斯蒂潘公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116670113-A | Compositions containing dialkylamino acid ester salts | 斯蒂潘公司 | 2023-08-29 | — | — | CN | disclosed |