Orthocresol

Orthocresol

SCHEMBL29060427

CC(C)O.Cc1ccccc1O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.50
ATM Q13315 1/20 0.50
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
ALDH1A1 P00352 5/20 0.45
TSHR P16473 4/20 0.45
LMNA P02545 3/20 0.45
TDP1 Q9NUW8 3/20 0.45
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
CA2 P00918 2/20 0.45
NPC1 O15118 1/20 0.45
CA12 O43570 1/20 0.45
GMNN O75496 1/20 0.45
EGFR P00533 1/20 0.45
FYN P06241 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orthocresol SCHEMBL16002 0.89
Orthocresol SCHEMBL29395276 0.89
Orthocresol SCHEMBL8710164 0.89 TRPA1 (0.60) TRPA1ATMGABRA1GABRB2CYP1A2
Orthocresol SCHEMBL170162 0.89 TRPA1 (0.60) TRPA1ATMGABRA1GABRB2CYP1A2
Orthocresol SCHEMBL10419161 0.89 TRPA1 (0.60) TRPA1ATMGABRA1GABRB2CYP1A2
Orthocresol SCHEMBL11426298 0.87 TRPA1 (0.48) TRPA1ATMGABRA1GABRB2CYP1A2
O-Xylene SCHEMBL9789704 0.87 CYP1A2 (0.51) TRPA1ATMGABRA1GABRB2CYP1A2
Orthocresol SCHEMBL6227977 0.86
Orthocresol SCHEMBL3407681 0.86
Orthocresol SCHEMBL2210412 0.86 ALDH1A1 (0.62) TRPA1ATMGABRA1GABRB2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116496144-A Method for producing thymol 诺琪蓥精细化工科技(大连)有限公司 2023-07-28 CN disclosed
CN-116253618-A Method for producing carvacrol by alkylation of o-cresol isopropanol/propylene 诺琪蓥精细化工科技(大连)有限公司 2023-06-13 CN disclosed