Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10551247 | 0.79 | PNP (0.42) | PNP | |
| SCHEMBL1808631 | 0.70 | ADORA3 (0.34) | — | |
| SCHEMBL27734016 | 0.68 | ADORA3 (0.35) | — | |
| SCHEMBL64349 | 0.66 | MAPK1 (0.43) | POLBHRH4MAPK1RECQL | |
| SCHEMBL667795 | 0.64 | PNP (0.61) | PNP | |
| SCHEMBL27464852 | 0.63 | KDM4E (0.42) | POLBHRH4MAPK1RECQL | |
| SCHEMBL16575386 | 0.62 | KDM4E (0.41) | POLBGAAHRH4MAPK1RECQL | |
| SCHEMBL11811150 | 0.62 | HRH4 (0.38) | POLBGAAHRH4RECQL | |
| SCHEMBL27857430 | 0.61 | CASP1 (0.55) | BACE1HRH4 | |
| SCHEMBL671139 | 0.61 | CASP1 (0.62) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116492347-A | Compound for activating AMPK and application thereof | 华安医学股份有限公司 | 2023-07-28 | — | — | CN | disclosed |