Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.64 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | RHEB | Q15382 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL764543 | 0.86 | F7 (0.72) | HRH4FLT3F7F3DAO | |
| SCHEMBL30310328 | 0.84 | F7 (0.74) | ALOX15HRH4PDGFRBFLT3F7 | |
| SCHEMBL671001 | 0.84 | F7 (0.74) | ALOX15HRH4PDGFRBFLT3F7 | |
| SCHEMBL23835754 | 0.82 | ALOX15 (0.69) | ALOX15HRH4PDGFRBFLT3F7 | |
| SCHEMBL31392730 | 0.81 | ALOX15 (0.72) | ALOX15HRH4PDGFRBFLT3KDM4E | |
| SCHEMBL31207838 | 0.80 | HRH4 (0.54) | HRH4PDGFRBFLT3 | |
| SCHEMBL3678805 | 0.80 | HRH4 (0.54) | HRH4PDGFRBFLT3 | |
| SCHEMBL19329742 | 0.80 | HRH4 (0.56) | ALOX15HRH4FLT3DAOMEN1 | |
| SCHEMBL30344312 | 0.80 | PLG (0.55) | ALOX15FLT3DAOKDM4EHPGD | |
| SCHEMBL16795745 | 0.79 | ALOX15 (0.61) | ALOX15HRH4PDGFRBFLT3F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |