Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.69 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.58 |
| ▸ | FLT3 | P36888 | 2/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729831 | 0.86 | F7 (0.72) | HRH4FLT3PDGFRBF7F3 | |
| SCHEMBL30310328 | 0.84 | F7 (0.74) | ALOX15HRH4FLT3PDGFRBF7 | |
| SCHEMBL671001 | 0.84 | F7 (0.74) | ALOX15HRH4FLT3PDGFRBF7 | |
| SCHEMBL29062810 | 0.82 | ALOX15 (0.64) | ALOX15HRH4FLT3PDGFRBF7 | |
| SCHEMBL25812914 | 0.81 | ALOX15 (0.67) | ALOX15HRH4FLT3PDGFRBF7 | |
| SCHEMBL24029234 | 0.81 | ALOX15 (0.67) | ALOX15HRH4FLT3PDGFRBF7 | |
| SCHEMBL5917452 | 0.81 | ALOX15 (0.71) | ALOX15HRH4FLT3PDGFRBF7 | |
| SCHEMBL6419283 | 0.80 | PLG (0.51) | ALOX15HRH4FLT3PDGFRBDAO | |
| SCHEMBL21983690 | 0.80 | FLT3 (0.60) | ALOX15FLT3PDGFRBDAORAB9A | |
| SCHEMBL25721366 | 0.80 | HRH4 (0.57) | ALOX15HRH4FLT3PDGFRBEIF4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252644-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2021-12-16 | — | — | WO | disclosed |
| US-11124497-B1 | Inhibitors of cysteine proteases and methods of use thereof | Pardes Biosciences, Inc. (US) | 2021-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11124497-B1 | Inhibitors of cysteine proteases and methods of use thereof | CTRL, CTSV, CTSL | ALOX15 2586/4885HRH4 3076/4885FLT3 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.