Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | MAP2 | P11137 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29062680 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL29063340 | 0.70 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL29613830 | 0.69 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL30149138 | 0.68 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL31161062 | 0.67 | ABCG2 (0.40) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL5994311 | 0.66 | ITGA4 (0.40) | MAPTHPGDTDP1ITGA4ITGB7 | |
| SCHEMBL23824623 | 0.65 | MEN1 (0.59) | MEN1KMT2A | |
| SCHEMBL23824620 | 0.65 | MEN1 (0.59) | MEN1KMT2A | |
| SCHEMBL21656359 | 0.64 | ITGA4 (0.40) | ALDH1A1KDM4EMTNR1AMTNR1BMEN1 | |
| SCHEMBL29484408 | 0.64 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |