Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | MAP2 | P11137 | 3/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613830 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTHSD17B10MAP2 | |
| SCHEMBL30149153 | 0.77 | MAPK8 (0.34) | ALDH1A1KDM4EMAPTMAP2AR | |
| SCHEMBL1786191 | 0.71 | KDM4E (0.53) | ALDH1A1KDM4EMAPTHSD17B10MAP2 | |
| SCHEMBL24189144 | 0.71 | KDM4E (0.53) | ALDH1A1KDM4EMAPTHSD17B10ABCG2 | |
| SCHEMBL8985827 | 0.70 | KDM4E (0.60) | ALDH1A1KDM4EMAPTHSD17B10ABCG2 | |
| SCHEMBL8054562 | 0.70 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTHSD17B10ABCG2 | |
| SCHEMBL7778483 | 0.70 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTHSD17B10ABCG2 | |
| SCHEMBL29062680 | 0.69 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTHSD17B10MAP2 | |
| SCHEMBL29484408 | 0.69 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTHSD17B10ABCG2 | |
| SCHEMBL6008353 | 0.68 | ABCG2 (0.65) | ALDH1A1KDM4EMAPTHSD17B10ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11541034-B2 | Nitrile-containing antiviral compounds | PFIZER INC. (US) | 2023-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11541034-B2 | Nitrile-containing antiviral compounds | ACE2, NOS2, EIF2AK2 | ALDH1A1 3238/4885KDM4E 1904/4885MAPT 3451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.