Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24113473 | 0.84 | CYP11B1 (0.34) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30008870 | 0.84 | CYP11B1 (0.34) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20535994 | 0.83 | GRIK1 (0.34) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL23147748 | 0.83 | GLA (0.35) | KMT2AMAPTMEN1GRM2MIF | |
| SCHEMBL20535997 | 0.83 | GRIK1 (0.34) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL18990057 | 0.83 | ALDH1A1 (0.38) | KMT2AMEN1LMNAALDH1A1CYP1A2 | |
| SCHEMBL18990052 | 0.83 | ALDH1A1 (0.38) | KMT2AMEN1LMNAALDH1A1CYP1A2 | |
| SCHEMBL18990053 | 0.83 | ALDH1A1 (0.38) | KMT2AMEN1LMNAALDH1A1CYP1A2 | |
| SCHEMBL19332373 | 0.81 | CES2 (0.33) | ALDH1A1 | |
| SCHEMBL18299918 | 0.81 | CYP1A1 (0.38) | KMT2AMEN1ALDH1A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |