Dymanthine

Dymanthine

SCHEMBL2906320

CCCCCCCCCCCCCCCCCCN(C)C.O=C(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES2 O00748 6/20 0.60
CES1 P23141 6/20 0.60
DNM1 Q05193 3/20 0.52
NAAA Q02083 1/20 0.50
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
JAK2 O60674 1/20 0.49
PAX8 Q06710 1/20 0.49
EGFR P00533 2/20 0.49
SIGMAR1 Q99720 1/20 0.49
THRA P10827 3/20 0.48
THRB P10828 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzil SCHEMBL4353316 1.00 CES2 (0.60) CES2CES1DNM1NAAARAB9A
Benzil SCHEMBL4349588 1.00 CES2 (0.60) CES2CES1DNM1NAAARAB9A
Benzil SCHEMBL4358252 1.00 CES2 (0.60) CES2CES1DNM1NAAARAB9A
Benzil SCHEMBL4359778 1.00 CES2 (0.60) CES2CES1DNM1NAAARAB9A
Benzil SCHEMBL4349851 1.00 CES2 (0.60) CES2CES1DNM1NAAARAB9A
Dymanthine SCHEMBL9189545 0.98 CES2 (0.58) CES2CES1DNM1NAAARAB9A
Benzil SCHEMBL9190633 0.98 CES2 (0.58) CES2CES1DNM1NAAARAB9A
Benzil SCHEMBL9183105 0.98 CES2 (0.58) CES2CES1DNM1NAAARAB9A
Benzoic Acid SCHEMBL613345 0.90 DNM1 (0.52) CES2CES1DNM1NAAARAB9A
Benzil SCHEMBL3855789 0.90 CES2 (0.60) CES2CES1NAAARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420579-B2 polytetrafluoroethylene, molybdenum disulfide or graphite as lubricant; a substrate containing polyamideimide resin and organic onium hydroxide compound modified sodium mica or sodium montmorillonite; n-methyl-2-pyrrolidone and xylene solvent; coating slilding surface, removing solvent KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2013-04-16 US disclosed
EP-1813663-B1 SLIDING MEMBER AND PROCESS FOR PRODUCING SLIDING MEMBER TOYOTA JIDOSHOKKI KK (JP) 2010-08-04 EP disclosed
US-20080194437-A1 Slide Member and Process For Producing Slide Member KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2008-08-14 US disclosed
EP-1813663-A1 SLIDING MEMBER AND PROCESS FOR PRODUCING SLIDING MEMBER KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2007-08-01 EP disclosed
EP-0379590-B1 GEL COMPOSITION AND NAIL COSMETIC SHISEIDO CO LTD (JP) 1995-09-20 EP disclosed
EP-0379590-A1 GEL COMPOSITION AND NAIL COSMETIC SHISEIDO COMPANY LIMITED (JP) 1990-08-01 EP disclosed