SCHEMBL29064067

SCHEMBL29064067

CCc1c[nH]c(CC)c1N

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.38
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
HTR1A P08908 1/20 0.30
HTR1D P28221 1/20 0.30
HTR1B P28222 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27284336 0.80
SCHEMBL23074728 0.78
SCHEMBL23403823 0.73 PGR (0.39) PGR
SCHEMBL27763269 0.71 PGR (0.38) PGR
SCHEMBL11353997 0.70 PGR (0.37) PGR
SCHEMBL4683112 0.67 GRIN2D (0.34) POLBHTT
SCHEMBL23890500 0.67 MPO (0.34) PGRHTR1AHTR1DHTR1B
SCHEMBL27669772 0.67 CCNC (0.31) HTR1AHTR1DHTR1B
SCHEMBL9655714 0.67 PGR (0.34) PGRHTR1A
SCHEMBL7450305 0.66 BRD4 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116693541-A Synthesis method of 4-chloro-5H-pyrrolo [3,2-D ] pyrimidine 安徽大学 2023-09-05 CN claimed
CN-116693541-A Synthesis method of 4-chloro-5H-pyrrolo [3,2-D ] pyrimidine 安徽大学 2023-09-05 CN disclosed