Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | PAM | P19021 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207976 | 0.89 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1PAMTDP1 | |
| SCHEMBL1434644 | 0.88 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1PAMTDP1 | |
| SCHEMBL10534818 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1PAMTDP1 | |
| SCHEMBL13291851 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1PAMTDP1 | |
| SCHEMBL4570308 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1PAMTDP1 | |
| SCHEMBL305415 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1PAMTDP1 | |
| SCHEMBL8566030 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1PAMTDP1 | |
| SCHEMBL14337318 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1PAMTDP1 | |
| SCHEMBL4911689 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1PAMTDP1 | |
| SCHEMBL245747 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1PAMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217564-A1 | COMPLEX PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE | XenoPort, Inc. (US) | 2010-08-18 | — | — | EP | disclosed |
| US-20090076147-A1 | COMPLEX PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE | XENOPORT, INC. | 2009-03-19 | — | — | US | disclosed |
| WO-2009033054-A1 | COMPLEX PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE | XENOPORT, INC. (US) | 2009-03-12 | — | — | WO | disclosed |
| EP-0236074-B1 | 2BETA-SUBSTITUTED THIOMETHYLPENICILLIN DERIVATIVES AND THEIR PREPARATION AND USE | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1992-01-08 | — | — | EP | disclosed |
| EP-0138523-B1 | PENICILLIN DERIVATIVES AND PROCESS FOR PREPARING THE SAME (11111) | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1987-08-19 | — | — | EP | disclosed |
| US-4668514-A | Penicillin derivatives | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1987-05-26 | — | — | US | disclosed |
| US-4562073-A | BETA-LACTAMASE INHIBITORS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1985-12-31 | — | — | US | disclosed |
| US-4529592-A | Substituted in position 2 with a (4,5-diester-1,2,3-triazol-3-yl)alkyl group | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1985-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076147-A1 | COMPLEX PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE | ADSL, SLC19A1, SLC25A21 | ALDH1A1 1514/4885MAPK1 4819/4885L3MBTL1 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.