Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29064836 | 0.81 | MKNK1 (0.46) | KMOMKNK1MKNK2DYRK1AHTR6 | |
| SCHEMBL25219879 | 0.80 | ABCB1 (0.47) | TP53ABCB1ABCC1CYP11B1CYP11B2 | |
| SCHEMBL29531325 | 0.80 | ABCB1 (0.47) | TP53ABCB1ABCC1CYP11B1CYP11B2 | |
| SCHEMBL1663904 | 0.74 | CYP11B1 (0.57) | ABCB1ABCC1CYP11B1CYP11B2KMO | |
| SCHEMBL17556134 | 0.74 | KIF18A (0.46) | — | |
| SCHEMBL652037 | 0.74 | HCAR3 (0.44) | ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL28799519 | 0.74 | HCAR3 (0.44) | MEN1KMT2A | |
| SCHEMBL17556135 | 0.74 | KIF18A (0.46) | — | |
| SCHEMBL652038 | 0.74 | HCAR3 (0.44) | ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL4704336 | 0.73 | ERN1 (0.56) | TP53ABCB1ABCC1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528867-A | Compounds for the treatment of Alzheimer's disease | 艾伯塔大学理事会 | 2023-08-01 | — | — | CN | disclosed |