Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 10/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 10/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL650663 | 0.85 | MAPT (0.45) | HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL29064874 | 0.81 | TP53 (0.48) | MKNK1MKNK2KMOPIM1PIM2 | |
| SCHEMBL19384226 | 0.76 | CYP2A6 (0.44) | MKNK1MKNK2KMOMEN1SLC22A12 | |
| SCHEMBL653107 | 0.74 | KCNH2 (0.49) | HDAC1 | |
| SCHEMBL650413 | 0.74 | KCNH2 (0.51) | HDAC3HDAC1HDAC2 | |
| SCHEMBL13522906 | 0.73 | MKNK1 (0.60) | MKNK1MKNK2KMOPIM1PIM2 | |
| SCHEMBL1512084 | 0.71 | KEAP1 (0.42) | HDAC3HDAC1HDAC2 | |
| SCHEMBL4066046 | 0.70 | HTT (0.44) | HDAC1 | |
| SCHEMBL247809 | 0.70 | KDM4E (0.38) | HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL27502701 | 0.70 | MKNK1 (0.46) | MKNK1MKNK2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528867-A | Compounds for the treatment of Alzheimer's disease | 艾伯塔大学理事会 | 2023-08-01 | — | — | CN | disclosed |